Friday 20 March 2015

IF IT FEELS LIKE STRESS IS KILLING YOU, THAT'S BECAUSE IT MIGHT BE

WHEN YOU FEEL FRAZZLED, SO DO YOUR ORGANS AND CELLS
 
Chronic Stress Has Consequences
Photograph and sculpture by Jason Freeny/Moistproduction.com
 
Chronic stress stems from many circumstances, such as poverty, a bad marriage, or long-term ailments. Its repercussions—elevated cortisol levels and inflammation—can wear us out, from the cellular level on up to our major biological systems.

Nervous System

The brain changes in response to experiences and the environment. This is especially true in childhood, when key structures—such as the amygdala, involved in the fight-or-flight center—develop. Extreme childhood adversity can alter these structures and impact mental health later in life. An estimated 30 percent of anxiety disorders are linked to early trauma. Research from Columbia University shows that orphans who spent their early years in institutional care can have abnormally large amyg­dalae, physical changes that can persist even after adoption.

Cardiovascular System

Both chronic stress and stress-related disorders, such as anxiety and depression, increase the risk for heart disease, although scientists are not entirely sure why. According to the American Heart Association, stress may indirectly influence cardiovascular health through high blood pressure as well as unhealthy behaviors, including overeating and smoking. And the shock of sudden, intense stress, such as the death of a partner, can rapidly weaken the heart, possibly because of a surge of stress hormones. The phenomenon is called broken heart syndrome.

Digestive System

The brain and the digestive tract are in constant communication, says Emeran Mayer, a gastroenterologist at UCLA. Unsurprisingly, chronic stress is associated with painful gastrointestinal issues. According to Mayer’s research, some patients with irritable bowel syndrome (IBS) show abnormal levels of cortisol and cortisol-stimulating hormones. People with IBS are also more likely to suffer from stress-related psychiatric disorders, including anxiety and depression.
30: Percent of U.S. adults who say stress strongly impacts their physical health; 33 percent say it strongly impacts their mental health

Cells

Nearly every cell has chromosomes, and the tip of each one is capped by a bit of genetic material; each time a cell divides, these telomeres shorten. When they run out, the cell dies. The chronically stressed have unusually short telomeres, putting them at risk for many age-related illnesses. The effects can be dramatic: In 2014, researchers found that disadvantaged 9-year-old boys had telomeres 19 percent shorter than those from more stable environments.

Immune System

According to research by Janice Kiecolt-Glaser, a clinical psychologist at the Ohio State College of Medicine, vaccines are less effective when we’re stressed and wounds take longer to heal. Research from Carnegie Mellon University shows that stress even makes us more vulnerable to the common cold. In 2012, the scientists found a likely culprit: In a healthy body, cortisol helps suppress inflammation. But the chronically stressed have consistently elevated cortisol levels, so the immune system grows resistant to the hormone, effectively ignoring it. Inflammation-causing proteins called cytokines—associated with developing a cold—then go unchecked.

Metabolic System

High cortisol levels boost the amount of fat around the belly. Extra abdominal fat may increase the risk for diabetes, which in turn may impair the stress response in the brain, says Antonio Convit, a psychiatrist at the Nathan Kline Institute for Psychiatric Research. The system that inhibits cortisol in the brain doesn’t work normally in people with type-2 diabetes. These patients also have blunted levels of cortisol when they wake up in the morning, as well as damage to the hippocampus, a brain region with concentrated cortisol receptors that is especially vulnerable to chronic stress.

How Does Stress Mess With Your Sleep?

Stress Hormones In The Blood
Katie Peek/Popular Science
Data source: P.W. Gold and G.P. Chousos, Molecular Psychiatry, July 2002
The stress hormone cortisol helps regulate sugar levels in the body. Cortisol levels vary throughout the day, but typically follow a circadian rhythm where they are highest in the morning, drop steadily, and then build up again overnight. Researchers from the National Institutes of Health found depressed patients tend to have abnormally high cortisol levels. Scientists still don’t know what this means, but it points to one of the many ways that stress-related disorders may interact with and disrupt normal body cycles.

Source: http://www.popsci.com/chronic-stress-it-could-be-killing-you?dom=tw&src=SOC

7 Job Interview Habits of Super Persuasive People

The next time you're looking for a job, give these powerfully effective interview habits a try.
BY PETER ECONOMY
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IMAGE: Getty Images
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A job interview is an opportunity to sell yourself. It is your opportunity to prove to the interviewer that you possess the skills necessary to take the company forward and that you are someone who can be trusted.
The most important persuasion tool you have in your entire arsenal is integrity.--Zig Ziglar
If the interview was successful, then you have clearly communicated what you have to offer, and have gained another friend--and hopefully a new job.
Persuasive people know how to prepare for and excel at interviews. Here are 7 things super persuasive candidates do to gain the trust and enthusiasm of the interviewer.
1. They study up
Prior to the interview, learn everything you can about the job you are applying for and the company. You can be far more persuasive when you understand and discuss how your skills align with those of the position you are interviewing for and the company's mission and future vision.
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2. They make the first seconds count
Researchers say you have about 7 seconds to make a great first impression. When you're doing an in-person interview, you need to look your best--dress professionally. Brush up on good body language practices. Always enter the interview with a cheerful, genuine smile along with a firm handshake. And, always greet the interviewer by name.
3. They develop a relationship
Tap into your emotional intelligence for interviews. Follow the lead of the interviewer and mirror his or her emotions. Is the interviewer shy or outgoing? Tone it down for the more reserved person and pump it up for the go-getter. Empathize with the interviewer and communicate your thoughts clearly. Strive for a relaxed, open and honest, friendly conversation as if you are speaking to a friend. The fact is, most people would much rather work with someone they personally like.
4. They zoom in on skills
Answer questions confidently and include specific examples of the skills you bring to the table. What is it that makes you special? How have you solved issues, handled customers, or worked alongside your co-workers in the past that demonstrate to the interviewer that you have the ability to be productive and an asset? Through your descriptive examples of past contributions and working relationships, you will draw a picture of the kind of person and worker you will be.
5. They don't push too hard
Even though you do have to sell yourself and let the interviewer know what you have to contribute, rein in the pushiness. If you get too pushy--speaking over the interviewer or becoming argumentative or confrontational--the interviewer will begin to tune you out and move to wrap up the interview as soon as possible--sending you on your way.
6. There are certain words they never use
You don't want your interviewer to come away from the interview not 100% sure you want the job. Ending too many sentences with a question as if you're seeking approval or saying things like, "I think," "I'm fairly confident," or "I'm pretty sure," is not going to leave the interviewer feeling confident about you and your prospects for working for their company.
7. They ask a lot of questions
Your interviewer will know you're listening to their every word when you ask appropriate questions following their pauses. This shows you genuinely care and want to learn more about the position and the company. Before your interview, be sure to have a few questions ready for that end-of-interview question, "Do you have any questions?" And, be prepared to ask the interviewer the same--you want to be sure before leaving that the interviewer knows you well and that there are no lingering questions.
PUBLISHED ON: MAR 20, 2015
 

How To Work Faster And Smarter

How To Work Smarter And Faster
Do you want to work faster and smarter? It can seem like an impossible task when your to-do list is as long as your arm and the work is still piling up, but the reality is that often the common methods we choose when working are not the most productive ones.
Check out 10 tips to help you to work smarter and faster.

1. Avoid Multitasking

Although a small amount of people are great at multitasking, for most people multitasking just reduces efficiency. Doing two tasks at once means you’re more likely to make little mistakes, as your brain is jumping from task to task. Focus on one task and fully complete it before moving on to the next one to produce better quality work in the same amount of time – or less!

2. Turn Off Your Non-Essential Technology

Nowadays technology is a huge part of most people’s working day, but it can really slow you down. When are you most productive during your working day? Whether it is first thing in the morning or early in the afternoon, schedule two hours to put your phone on silent and switch off your email notifications.
You can ring and email people back once the time is over, but during that time you will work faster because you chose to only focus on your work.

3. Shut The Door While You Work

Many companies have an open door policy at work to encourage openness. However, if you want to work faster, close your door for at least a few hours during the day. Interruptions and distractions are much more likely to happen if the door is open, so cut out the temptation if you want to have an extra productive day.

4. Create A Personalized Structure

Most people tend to work faster and smarter if they have a structure. Remember that everyone is different; something that works well for your boss may not work as well for you.
Think about when you are at your most productive, and try to plan your working day around that time. Remember to plan responding to calls and emails, too; most people simply do this throughout the day, slowing down their work and making themselves less efficient.

5. Set A Finish Time

If you know you will be leaving the office at 6, it will help you work more efficiently until then. Knowing you have a deadline will help you to prioritize tasks, as well as making you less likely to procrastinate.

6. Pre-Plan Breaks

Taking short breaks helps you to stay focused so that you work faster and smarter. If you don’t schedule them into your day, you can end up taking breaks that are too long, or not taking any at all, which can result in you becoming stressed or working to a lower standard.
Try to spend your break productively – stretch your legs and make a cup of tea, rather than logging onto Facebook.

7. Remember Some Tasks Are More Important Than Others

Many people feel like they have put too much effort into a meaningless task at work at least once. Try to remember this when you decide how important each of your jobs are; some are career-changing and some will never be noticed.
If a task only takes 10 minutes, don’t try to make it amazing and spend half an hour on it – it won’t become any more important. Instead, focus on the tasks that you know matter.

8. Set A Bedtime And Keep To It

As well as a work schedule, having a sleep schedule for the days you work will help you to work faster and smarter. You will work more efficiently if you have slept well, so set a bed time that means you get enough sleep, and turn off the internet on your phone so you stick to it.

9. Keep Your Desk And Laptop Clutter Free

The less clutter you have, the less stress you will feel. This especially applies to work when your stress levels are often higher. Keep a clear desktop and desk to make it easier for you to find anything you need, so you don’t have to waste time and you can keep a clear head.

10. Make Sure You Have Everything You Need

Planning ahead and making sure you have everything you need will help to save you time and help you to work faster. Before you start your working day, make sure your phone and laptop are charged, and that you have all of the equipment you need. Having to look for a pencil, or charge your laptop could take quarter of an hour out of your day, and you may struggle to refocus on work afterwards.
 

Thursday 19 March 2015

The Brain Stimulator Method Review

The Brain Stimulator Review – We know that  persons brain is the soul of the our central nervous system. It controls unconscious activities such as breathing, digestion, and heart beat, which are also known as automated functions of the physique. This organ also regulates other conscious actions that are regarded as greater order activities like thinking, abstraction, and thought. A persons brain is superior to any other brain associated with a other living varieties that are known to mankind.
This is a unique program, has been clinically proven to help prevent and reverse brain issues such as dementia and considerably strengthen mental power, memory and concentration. This program was developed by 2 highly experienced researchers Prof. J. Wilson and Doctor. Richard Humphrey after many years of relentless off-grid study and clinical trials.
brain stimulation techniques
This particular method is so extraordinary and efficient that it has practically been banned in a few jurisdictions because it’s users tend to have intimidating intellectual capabilities. This program comes as PDF prepared eBook available for purchase on the internet. The PDF documents contain several easy brain exercises in addition to how they are performed to create the beneficial effects upon brain health.
Is Brain Stimulator Method Really Works?
The program has become very popular that an estimated more than 39K people and keeping track of use it daily with every confessing its efficacy. This particular controversial brain trick has been clinically proven in order to drastically improve greater brain functions including intellectual functions, and promote and regrow nerves permanently.
The Brain Stimulator Method may return your brain overall performance to the useful many years (20s) not issue your current age or even cognitive condition. Actually, the unique brain exercises within the eBook have been proven to enhance rejuvenate brains intellectual performance in just a fortnight. You will be surprised to understand that the developer from the method is a 104-year old neuroscientist that recovered from Alzheimer’s illness in just 14 days.
Advantages Of Brain Stimulator Method Program:
  • The method is simple, however highly effective. It can be used through anyone of any age as well as cognitive status. It is possible from the comfort of your home.
  • .The method is very secure as no medicines, mechanical stimulation or any other weird methods are utilized.
  • It will help to prevent and change brain issues such as dementia, as well as effortlessly improve storage, concentration and focus. This particular effects are long term
  • Brain Stimulator Method is backed by many years of off-grid research by top neuroscientists and supported by many peer reviewed healthcare journals.
  • The eBook is actually competitively priced and it possesses an unbelievable discount. Apart from, it comes with 60-day money back guarantee, if you are not satisfied with the outcomes.
Dis-advantages Of Brain Stimulator Method Program:
Apart from advantages, here is some cons of this method:
  • There is very little unfavorable thing to say relating to this eBook because it is packed with so many benefits you will simply find out after using the product.
  • One problem with this eBook is the fact that very little information is on its mechanism associated with action because of copyright laws issues. Besides, pharmaceutical drug companies and health professionals are fighting to keep their stance.
Final Thoughts About This Method:
If you or your family member has been suffering from the signs and symptoms of declining brain wellness such as forgetting people’s titles, forgetting your secrets, difficulty communicating, lack of balance and co-ordination, personality changes and have already been diagnosed with Alzheimer’s illness or you want to enhance your brains performance then your Brain Stimulator Method is the way to go. Go to their official web page and purchase the product. You’ll wake up to find a brand new you.

Wednesday 18 March 2015

Measuring dementia risk: Now there's a number for that, too

Neurologists have developed a test to help predict the risk of developing mild cognitive impairment, or MCI. People with MCI are much more likely to develop Alzheimer's disease. (AP Photo/Charles Dharapak)
By MELISSA HEALY
March 18, 2015, 3:18PM
Few of us would be eager to have a future of dementia revealed to us while we are still sharp. But there are powerful arguments for knowing -- as early as possible -- if we are at risk.
True, there is currently no medication that can slow or reverse Alzheimer's disease. But more and more research suggests that long before dementia sets in, nearly imperceptible changes are happening in the brain. Researchers believe that the key to bending dementia's arc will be to intervene either before behavioral symptoms set in or when they are still very mild.
And if researchers are to find therapies for dementia that work, they will need clinical trial participants who are brave enough both to learn they are at risk early and to submit to experimental treatments.
A new study, published Wednesday in the journal Neurology, distills a way for physicians and their patients, in the course of a regular office visit, to measure an individual's risk of developing mild cognitive impairment, or MCI. In a population of 1,449 Minnesotans 70 to 89 years old, the resulting algorithm helped identify individuals whose scores were in the top 25% and who were more than seven times more likely to develop MCI than those in the bottom quartile of risk.
Patients diagnosed with MCI are at greatly increased risk for Alzheimer's disease: studies suggest that each year, 10% to 15% of those with MCI will progress to Alzheimer's. So knowing one's risk for developing MCI may be one of the earliest ways to detect future Alzheimer's patients at a point when still-experimental therapies might work.
“This risk scale may be an inexpensive and easy way for doctors to identify people who should undergo more advanced testing for memory issues or may be better candidates for clinical trials,” said Dr. Ronald C. Petersen, a neurologist at the Mayo Clinic in Rochester, Minn., and lead author of the study.
Until now, the most powerful single marker for Alzheimer's disease risk has been whether an individual is a carrier of a specific variation of the APOE-4 gene. The current study finds that a person's APOE-4 carrier status can further refine his or her risk for mild cognitive impairment. But the risk measure devised here also takes into account other contributors to risk that can be easily gleaned during an office visit.
For men and women alike, a diagnosis of diabetes contributes powerfully to the risk of developing mild cognitive impairment, particularly if the individual is younger than 75 and has developed the metabolic condition already. Two other hefty contributors to MCI risk are high levels of agitation, anxiety or apathy, as measured by a patient's response to a battery of neuropsychiatric questions.
A history of alcohol problems, self-reported memory problems and failure to complete at least 12 years of education also contribute to a man or woman's risk of MCI. And a history of stroke or atrial fibrillation nudged risk scores up modestly.
Some risk factors are specific to a patient's gender.
For women, being a current smoker, or having had worrisome cholesterol numbers, high blood pressure or diabetes in midlife drive risk of MCI higher.
Could a blast of sonic waves restore memory lost to Alzheimer's disease?
Could a blast of sonic waves restore memory lost to Alzheimer's disease?
For men, being widowed or having never married raises MCI risk. And having been obese at anytime (body mass index of 30 or above) also drive up the likelihood of MCI. In men, walking carefully or unsteadily -- slow gait -- also raises risk.
When added to this constellation of risk measures, APOE-4 carrier status proved only to confer moderately increased risk of developing mild cognitive impairment.
In an accompanying editorial published in Neurology, Dr. Timo Grimmer and Alan B. Zonderman cautioned that, until the current findings have been replicated in a larger and more ethnically and educationally diverse sample, physicians would be "well advised to utilize the risk score with caution."
But Grimmer, an Alzheimer's disease researcher, and Zonderman, a cognitive neuroscientist at the National Institutes of Health, said the study offers physicians and their patients some key guidance on how to lower risk of dementia, starting in midlife: for women, avoid or stop smoking, and for men, stay trim.
For both sexes, the latest research underscores the importance of keeping alcohol consumption moderate or quitting altogether. And at all costs, head off the development of type 2 diabetes, a metabolic condition closely linked to obesity.
 

Tuesday 17 March 2015

Why men lose their memory younger than women

Men are affected by memory loss earlier than women, according to a study. Why does it happen and what can we do to stave it off?

'This type of decline happens in other organs of the body, so why shouldn’t it happen with the brain?'
'This type of decline happens in other organs of the body, so why shouldn’t it happen with the brain?' Photo: ALAMY
 
Men over 40 have worse memories than women of the same age, according to a study carried out by American scientists.
The research showed that the hippocampus area of the brain, which is key to memory storage, normally began shrinking from the age of 30 in both sexes, but tended to decline more rapidly in men.
Dr Clifford Jack Jr. of the Mayo Clinic and Foundation in Minnesota said it was still unclear why this was, but might be because the female hormone oestrogen protects women’s brains from neuron damage until later in life.
The study - of 1,246 people between the ages of 30 and 95 - also showed that memory lapses are felt by everyone once they reach middle age, and those who experience them should not necessarily worry about the onset of dementia.
“A decline in memory is something that happens to everyone,” Dr Jack said.
“This type of decline happens in other organs of the body, so why shouldn’t it happen with the brain?”
Another academic said the study would help with our understanding of dementia.
Dr Charles DeCarli of the University of California at Davis, Sacramento, said: "Understanding the basic biology of these early processes are likely to substantially inform us about ways in which we can maintain cognitive health and optimise resistance to late-life dementia."
In common with previous studies, this new research found that men had lower average scores than women on verbal mental tests even as teenagers. Women tended to keep the advantage in this area until they went through the menopause or hit their 50s.
Previous studies have suggested Champagne, cups of cocoa and learning another language could help stave off memory loss.

Others have put forward regular exercise or even “a sharp pinch” as the secret to enjoying total recall even into later life.

Source: http://www.telegraph.co.uk/men/active/mens-health/11476932/Why-men-lose-their-memory-younger-than-women.html

10 reasons your belly fat isn’t going away

Muffin_Top_640.jpg
A little bit of belly fat is actually good for you: it protects your stomach, intestines, and other delicate organs. But too much fat is anything but healthy. Extra fat cells deep in your abdomen (aka visceral fat) generate adipose hormones and adipokines—chemical troublemakers that travel to your blood vessels and organs, where they cause inflammation that can contribute to problems like heart disease and diabetes. The good news? Every pound you shed can help reduce your girth.
"Once women start losing weight, they typically lose 30 percent more abdominal fat compared with total fat," said Dr. Rasa Kazlauskaite, an endocrinologist at the Rush University Prevention Center in Chicago.
Even better, the choices you make every day can supercharge your ability to burn belly fat. Here are 10 common pitfalls—and ways to undo each one.
You're on a low-fat diet
To shed belly fat, it's good to eat fat—specifically monounsaturated fatty acids (MUFAs). When researchers in one study asked women to switch to a 1,600-calorie, high-MUFA diet, they lost a third of their belly fat in a month.
 
"MUFAs are satiating, so they help you eat fewer poor-quality foods," said Dr. David Katz, director of the Yale Prevention Research Center.
Belly blaster: Have a serving of MUFAs—like a handful of nuts, a tablespoon of olive oil, or a quarter of an avocado—with every meal and snack.
You've been feeling blue for a while
Women with depressive symptoms were far more likely to have extra belly fat, found a recent Rush University Medical Center study. That may be because depression is linked to reduced physical activity and poor eating habits.
Belly blaster: Exercise! "It improves levels of brain chemicals that regulate metabolism of fat, as well as your mood,"Kazlauskaite said.
This enhances your motivation to do other things that help ward off depression, like seeing friends. But if you're so bummed out that you don't want to do things you used to enjoy, it's time to seek the help of a therapist.
Your food comes from a box
Simple carbs (like chips) and added sugar (in items like sweetened drinks) cause your blood sugar to spike, which triggers a flood of insulin—a hormone that encourages your liver to store fat in your middle.
Belly blaster: Instead of focusing on cutting out junk, center your efforts on adding in healthy fare (think extra servings of vegetables at each meal). As Katz said, "Filling your tank with high-quality fuel thwarts hunger."
You're skimping on the miracle mineral
Magnesium regulates more than 300 functions in the body. No surprise, then, that a 2013 study found that people who consumed more of it had lower blood sugar and insulin levels.
Belly blaster: At least twice a day, reach for magnesium-rich foods such as dark leafy greens, bananas, and soybeans.
You're hooked on diet soda
A study in Obesity found that diet soda drinkers were more likely to have a high percentage of fat in their bellies. The researchers think that diet drinkers may overestimate the calories they're "saving," and then overeat.
Belly blaster: If you're not ready to kick your habit, the researchers suggest reducing the number of food calories in your diet.
You love burgers
When Swedish researchers gave one group of adults 750 extra daily calories, mainly from saturated fat, and another group the same amount of calories but mostly from polyunsaturated fatty acids (PUFAs) for seven weeks, the saturated fat group accumulated two times as much visceral fat.
Belly blaster: Dine on fatty fish like salmon or trout once a week to get a good dose of PUFAs. The rest of the time, reduce your intake of red meat and opt instead for protein low in saturated fat, such as legumes and chicken.
You think girls don't get beer guts
According to a 2013 Danish study, beer may indeed be linked with abdominal obesity. And though beer appears to have the greatest impact, wine won't save you from a spare tire: One study found that the amount of alcohol of any type that women drank contributed to weight gain.
Belly blaster: Stick with seven or fewer alcoholic beverages a week. Light to moderate drinkers are the least likely to carry excess weight anywhere, shows a recent Archives of Internal Medicine study.
You can't recall when you last said "om"
Menopause-related hormonal changes (which typically begin in your 40s) make it harder to shed stomach pudge—but vigorous yoga can help offset the effects. A 2012 study found that postmenopausal women who did an hour-long yoga session three times a week for 16 weeks lost more than 1/2 inch around their waists.
Belly blaster: Not a fan of Sun Salutations?
"Take an hour to do something nice for yourself," which could help control your stress hormones, advised Dr. Sheila Dugan, a physical medicine and rehabilitation specialist in Chicago.
Your meals are beige
Brightly colored fruits and veggies are loaded with vitamin C, which reduces cortisol. What's more, a recent study in The Journal of Nutrition showed that people who ate more of the nutrients in red, orange, and yellow produce had smaller waists as a result.
Belly blaster: Add color to your plate by topping fish with a mango salsa, or throw diced red pepper into your turkey meatballs.
Your sweat sessions don't involve sweat
Research has shown that high-intensity interval training, or HIIT—bursts of vigorous activity followed by short periods of gentle activity or rest—boasts belly-shrinking benefits.
"High-intensity exercise seems to be more effective at reducing insulin, triglycerides, and cortisol, and it burns more calories in less time, too," noted Shawn Talbot, PhD, a fellow of the American College of Sports Medicine.
Belly blaster: If you enjoy biking or running, for example, accelerate to a pace that makes it hard to talk for two minutes; then slow down for a minute, and repeat until you're done. Like resistance training? Try a series of moves like squats or push-ups for two minutes each with a 60-second break between them.

Source: http://www.foxnews.com/health/2015/03/17/10-reasons-your-belly-fat-isnt-going-away/

Why dementia sufferers have something to sing about

More of us are sharing our experiences of this disease, and fresh ideas are gaining ground

Prunella Scales and Timothy West in happier times
Enormous courage: Prunella Scales and Timothy West in happier times Photo: Srdja Djukanovic
 
We change throughout our lives. Mostly we don’t notice, or take it for granted. Women scrutinise the mirror for wrinkles from their mid-twenties, but however much Botox and age-defying cream they use, the changes wrought by time will eventually have their way. Men notice their midriffs starting to bulk up and that they aren’t as fleet of foot as they once were. The inevitability of change comes all the more forcibly as you get older.
Most people nowadays know someone with some form of dementia. I have several friends who are on the dementia spectrum: some early onset, others further along the way. One of them is the actress Prunella Scales, who was courageous enough to talk on the programme about her condition. The impact of what she and her husband, the actor Timothy West, had to say is proving to be important. Ever since the programme I have been inundated with emails and tweets expressing admiration for them, but also joining in the debate about how we should treat dementia sufferers.
Messages and reports are reaching me from, among other places, Edinburgh, Manchester and Fife. I am told that the herb Huperzia serrata has properties that can help: I look it up on the web and find it marketed as “Anti-Alzheimer’s Disease”. More seriously, I hear from a medical herbalist in Reading who believes that it “promises to hold much benefit in the delay and early onset” of dementia. Unfortunately, she can’t get funding for a rigorous scientific study because the relevant bodies in this country tend to steer clear of medicinal herbs.
I hear from Manchester, where I’m told university work is progressing on a generic drug, licensed for shingles but not, so far, for Alzheimer’s. An application for trials was turned down by the Medical Research Council, despite, my correspondent tells me, favourable referee reports. I myself am in no position to judge, but I’m impressed that new thinking is going on around the subject.
I also hear from a man called Peter, who, after a career in clinical psychology, was diagnosed at the age of 76 with “early, very mild Alzheimer’s disease”. He took a positive attitude to living well with it and went on to pass a degree-level module in Italian at the Open University, and become one of the Alzheimer’s Society’s research volunteers. Then I am sent a booklet called Rethinking Communication, written by two dementia psychologists about what they call “adaptive interaction”, and how it can bring comfort to those locked away in silence. I see a video on Facebook that bears this out. Clearly there is much going on among sufferers, their carers and those struggling to research how the condition can be ameliorated.
What I realise from all these responses is the need for society as a whole to become more open and understanding of dementia, to embrace its sufferers within the community and not leave them isolated and alone. One town that is becoming dementia-friendly is Crawley. Training is offered to bus drivers, shopkeepers and waiters about how to relate to those with the condition. Dementia sufferers are invited to schools to talk to the children. We need more of this: more engagement, more social and personal commitment. And above all more political will.

Source: http://www.telegraph.co.uk/news/health/elder/11305141/Why-dementia-sufferers-have-something-to-sing-about.html

52 Ways to Control and Conquer Stress

Stress

It's hard to say, exactly, what the worst part about stress is. Is it the tightness that starts somewhere around your solar plexus, then extends out to your toenails, earlobes, and cerebellum? Is it randomly snapping at innocent—and, occasionally, quite guilty—coworkers and loved ones? Is it sobbing quietly behind the closed door of a men's-room stall?
Uh, sorry, did we say that last one out loud?
The point is, stress attacks in all sorts of ways—which means that if you want to control it, contain it, conquer it, you need to fire back in kind. That's why we've spent the past several months devouring studies and cross-examining experts to find the 52 best stress-busting tips of all time. We won't lie—it was a bear of a job, and there were desperate moments when we thought we actually smelled smoke coming from the old cerebellum (see quiet sobbing in men's room, above). But when we sat down and read the advice we'd compiled—and then started following it—we suddenly felt much, much better.
 
Soon you will, too.
Drink More OJ
Researchers at the University of Alabama fed rats 200 milligrams of vitamin C twice a day and found that it nearly stopped the secretion of stress hormones. If it relaxes a rat, why not you? Two 8-ounce glasses of orange juice daily gives you the vitamin C you need.
Put a Green Dot on Your Phone
This is your secret reminder to take one deep breath before you answer a call, says Susan Siegel, of the Program on Integrative Medicine at the University of North Carolina school of medicine. Not only will you feel better, but you'll sound more confident.
Spend Quality Time with a Canine
Yours or someone else's. According to research at the State University of New York at Buffalo, being around a pet provides more stress relief than being around a two-legged companion. As if we needed a study to determine that.
Go to Starbucks—with Your Coworkers
Researchers at the University of Bristol in England discovered that when stressed-out men consumed caffeine by themselves, they remained nervous and jittery. But when anxious men caffeine-loaded as part of a group, their feelings of stress subsided.
Shake It Out
When you're facing that big-money putt, shake out your fingers, relieving the tension in your forearms, hands, and wrists and shifting your focus to the only thing you can control: your preshot routine. You won't think about making—or missing—the shot, says Alan Goldberg, Ed.D., a sports-psychology consultant in Amherst, Massachusetts.
Listen to Music at Work
And make it the blandest playlist you can create. According to a study at Pennsylvania's Wilkes University, Muzak lowers your stress levels at work, while also reducing the risk of the common cold. We knew Celine Dion had a purpose.
Shut Up and Smile
Freaking out about a speech? Smile, look at the audience, and keep quiet for 2 seconds, says T.J. Walker, president of Media Training Worldwide. It'll slow you down and create the impression that you're relaxed and in control. The audience will then feel more comfortable, leading you to actually be relaxed and in control. Now start talking. Unless you're a mime. In that case, as you were.
Talk with Your Hands
To keep calm in a job interview, rest your arms on your lap, with your elbows bent slightly, and have your fingers almost touching, says Walker. This will keep your body relaxed, which will keep your tone conversational.
Run Fast
Bike hard. Punch the heavy bag. And we don't mean your mother-in-law. A University of Missouri at Columbia study found that 33 minutes of high-intensity exercise helps lower stress levels more than working out at a moderate pace. What's more, the benefits last as long as 90 minutes afterward.
Hit the Sauna After Your Workout
In an Oklahoma State University study, those who combined sauna use with group counseling had greater stress relief, feelings of relaxation, and sense of accomplishment compared with those who only had their heads shrunk.
Remember the Lyrics to Your Favorite Song . . .
. . . name at least 30 states, or assemble the All-Time Band of Guys Named James (the James Gang doesn't count). In other words, give your mind any all-consuming challenge, as long as it has a definite finish—unending problems cause more stress, says Toby Haslam-Hopwood, Psy.D., a psychologist at the Menninger Clinic in Houston.
Lay The Journey to Wild Divine
It's a CD-ROM game that works like this: Three biofeedback sensors worn on your fingers sense your stress level and translate it into your ability to perform tasks such as levitating virtual balls or controlling birds in flight. The more you play, the more mastery you gain over your emotions. Go towilddivine.com for more information. It sells for about $300.
Find a Breathtaking View
Now take a breath—and a good long look. You'll walk away from the brink with a sense of context and a bigger perspective, which will make the 5,000 things on your to-do list seem less daunting, says Allen Elkin, Ph.D., director of the Stress Management & Counseling Center in New York City.
Imagine You're on a Game Show
Try Who Wants to Be a Millionaire. When dealing with a screaming child in a car or any other acutely stressful situation, ask yourself how long you could listen to it if someone gave you $100,000, suggests Elkin. Suddenly, it's not so awful, is it?
Say You're Sorry
What, now the kid is screaming on a crowded airplane? Immediately apologize to everyone around you. By acknowledging that you may have made a mistake or hurt someone else, you can help clear the air, and that will reduce your stress level, says Charles Emery, Ph.D., an associate professor of psychology at Ohio State University.
Forgive
Now someone else's kid is screaming on a crowded airplane? And the mom is too wrapped up in this week's People to do a thing about it? Let it go, says Carl Thoresen, Ph.D., a psychologist at Stanford University. Realizing that you can't control someone else's behavior is difficult, but it's one of the best ways to destress.
Add Trees to Your Commute
Even if it takes you out of your way, it may make your ride less stressful. An Ohio State University study found that scenic drives were more calming than those involving strip malls and endless, disheartening asphalt.
Water a Plant
It's nurturing, it doesn't take up much space, and for 10 seconds, the world is not about you, which can be a huge psychological relief, says Elkin.
Ditch the Dingy Shower Curtain
And hang up something in a cool color like green or blue. According to Leonard Perry, Ph.D., an extension professor at the University of Vermont, cool hues are more soothing.
Schedule Medical Tests for Early Morning
Rather than spend the entire day anxious about an afternoon DRE, get fingered first thing in the a.m., when your cortisol levels are already naturally elevated, says David Spiegel, M.D., medical director of the Stanford Center for Integrative Medicine.
Meditate
Researchers at West Virginia University found that 35 participants who underwent "mindfulness meditation" saw a 44 percent reduction in psychological distress over 3 months. Just sit quietly for 10 minutes a day and focus on your breathing.
Find a Shoe-Shine Guy at the Airport
Walking lessens the frustration, and having a destination keeps your mind busy, says Michael Nuccitelli, Psy.D., a psychologist in Brewster, New York. You'll also have fine-looking shoes. And if this magazine has taught you anything, it's that ladies notice fine-looking shoes.
Call Your Travel Agent When . . .
. . . the boss calls you on the carpet.
Not only will you see the calming light at the end of a stressful tunnel, but your work will improve, says Srini Pillay, M.D., director of the Panic Disorders Research Program at McLean Hospital in Belmont, Massachusetts. Schedule the trip far enough ahead so it doesn't look like a reaction to the blowup.
Put a Hole in a Tennis Ball and Squeeze
Let the tension build up in your hand and the rest of your body, then release. This increases relaxation, Elkin says. Tennis balls are those yellowy things people hit around in the '70s and '80s.
Have Sex
Either with or without a partner. An orgasm releases beta-endorphins, the body's natural, less punk-rock version of heroin, so you'll definitely be feeling no pain, says Nuccitelli.
Play in the Dirt
Want to be the MVP of your softball league? When you're batting with the winning run on base, step into the box, pick out a mark in the dirt, and rub it out with your foot, says Goldberg. By symbolically "rubbing out" the past, you'll focus on the now—and not the last three times you struck out.
Stop Checking Your Portfolio
A study of Hong Kong investors found that those who keep a close eye on their stocks are more likely to be stressed out. Instead, get educated at a site like fool.com. Those who saw the bigger financial picture felt better.
Call a Pal—on the First Day of a New Job
And take several brief breaks throughout the day. By slowing things down, you'll feel as if you have more control in the new work environment, and that will ultimately reduce your stress level, says Emery.
Add 10 Minutes to Your ETA
When you're stuck in traffic, call whomever you need to and tell them you'll be late—but add 10 minutes to your revised arrival time, says Dr. Pillay. Missing deadlines is stressful. Avoid missing another one.
Hold Your Girlfriend's Hand for 10 Minutes
A University of North Carolina at Chapel Hill study found that loving contact lowers blood-pressure and heart-rate responses in stressful situations. In the study, those who experienced contact were nearly twice as relaxed as the unloved, untouched group.
Give Up the Butts
Researchers on the European Board for Research on Nicotine and Tobacco found that nicotine suppresses the stress-fighting hormone serotonin. It also triggers the release of the chemical dopamine, which stimulates pleasure centers in the brain. The problem: Dopamine levels soon drop and leave the body craving more, making you incredibly anxious—and jonesing another smoke.
Remember, It's Not About You
Before you fire someone, depersonalize the situation. He's getting axed because he screwed up or the company has to shed weight. It's not your fault, Nuccitelli says. Give yourself 15 minutes beforehand to say this, until it becomes foremost in your thoughts.
Eat Whole-Wheat Pasta Before a Date
A study in Alcoholism: Clinical & Experimental Research shows that taking in complex carbohydrates can help boost the brain's levels of the hormone serotonin. Impaired serotonin levels can lead to depression, anxiety, and aggression—none of which is attractive on a date.
Resand that Old Dresser
Harness your excess stress by tackling a large project that requires a lot of physical energy. "Next time you start thinking, I'm stressed, replace that thought with I have a high energy level—then use the energy," says Jay Winner, M.D., author of Stress Management Made Simple. Note: Foreplay counts as a large project requiring a lot of physical energy.
Press Your Dress Shirts
The repetitive motions of ironing can send you into a trancelike state, which puts your brain on autopilot and helps block out stressful thoughts, says Dr. Winner. And no more unsightly wrinkles!
Turn It into a Game
When you sense customer service/human resources/the insurance company starting to screw you, say, "Oh, I get it. They're trying to screw me. Let's see what happens." Now it's a game, not a personal attack. Your stress will go down with the shift in perspective, says Reef Karim, M.D., a psychiatrist at UCLA Neuropsychiatric Institute.
Predict the Future
Whether it's a woman you have to dump or a coworker you have to confront, anticipate all the outcomes—tears, screaming, excuses. Familiarity prevents surprises, and that slashes stress, Dr. Karim says.
Make a Schedule
If the boss suddenly dumps a big project on you, try not to say, "I can't do this. I'm gonna get fired." (Try particularly not to say this in front of your boss.) Instead, present him with a schedule outlining when things can be done. What was overwhelming is now under control and open to negotiation, says James Blumenthal, Ph.D., a psychologist at Duke University.
Stay Awake Till 3 a.m
Too stressed to sleep? Vow to stay awake for 30 minutes. You've removed the stress of not being able to fall asleep—which may relax you enough that you will fall asleep, says Bill Roedel, Ph.D., a professor of psychology at Bastyr University in Kenmore, Washington.
Get Out of Debt Denial
Maxed-out MasterCard? Do the no-duh obvious: Meet with a financial planner. According to a Virginia Tech study, those who received credit counseling saw their overall stress level move from "severe" or "overwhelming" to "moderate" or "low" 1 year later.
Drive Like Keith Moon
Not drunk, but drumming on your dashboard. A study in Advances in Mind Body Medicine showed that group drumming alleviated stress. A drum solo may bring similar benefits.
Find the Good
Missed a deadline? Appreciate what you learned about planning ahead. Kids kept you up with a stomach flu? Be grateful this is the only health woe facing your family. By finding the good in a stressor, you reduce the intensity, says Dr. Winner.
Buy the Right Kind of Christmas Tree
That is, not an artificial one. When the holidays approach, pick up a real Norway spruce or Scotch pine. The natural scent of pine is calming, says Janis Burke, an aromatherapist at Washington State University's college of nursing.
Rest Between Workouts
Overtraining can actually cause stress. According to a report in the Journal of Strength and Conditioning Research, excessive training elevates cytokine levels in the blood, which tells the brain to raise cortisol levels, which tells you to freak out!
Climb a Mountain
Unless you're afraid of heights. According to a Texas A&M study, rock climbers and hikers have lower stress levels than their less rugged peers. The same skills that help people navigate successfully through the wilderness may help them keep calm when navigating the office.
Hike the High Country
High-altitude air is charged with negative ions. "When you breathe them in, it's relaxing and rejuvenating," says Mark Liponis, M.D., medical director at the Canyon Ranch Spa in Lenox, Massachusetts.
Go for a Swim
During the day, your legs collect pools of lymphatic fluid, an excess of which can make you uncomfortable and irritable—until you take a dip, says Dr. Liponis. "It squeezes all the lymphatic fluid back into your heart and out through your kidneys," he says. Think of the postswim pee as liquid stress leaving your body.
Hold Your Tongue
When your annoying colleague decides to be annoying once again, tell yourself, I choose to be calm, says Siegel. Ah, now it's a choice, and you choose to be master and commander of the ship.
Unwind Online
Instead of surfing for porn at work, stay employed and go tostressremedy.com. Shut your door, turn up your speakers, and click on "Relax Now" for a 6-minute, audio-guided relaxation exercise based on deep breathing and meditation.
Grab Your Ears
Tug your lobes (lightly) and move them in circles in opposite directions for a count of 10, says Elizabeth Cornell, of the Muscular Therapy Center in New York City. The motion moves the tentorium membrane in your head, which can relieve stress. You'll also be in fighting shape for charades.
Chug a Big Glass of Cold Water
Because? Not sure, says Nuccitelli. "I have no idea why it works, but I've seen it be effective." Besides, when is it bad to be hydrated?
Find Your Smell
Aromas trigger strong connections to good memories, says Haslam-Hopwood. Unless you were forced to work in a bakery as a child, fresh bread works. Vanilla and orange are other options.
 

If you remember this story, another memory will die off

Remembering makes us forget as the process of recall actually causes people to lose other memories

A nerve cell
A nerve cell. Photo: Alamy
 
Researchers at Birmingham University and the MRC Cognition and Brain Sciences unit in Cambridge showed how intentional recall actually leads us to forget other competing experiences that interfere with retrieval.
Put simply, the very act of remembering may be one of the major reasons why we forget.
The research, published in the journal Nature Neuroscience, is the first to isolate the adaptive forgetting mechanism in the human brain.
The brain imaging study shows that the mechanism itself is implemented by the suppression of the unique cortical patterns that underlie competing memories.
Dr Maria Wimber, of Birmingham University, said: “Though there has been an emerging belief within the academic field that the brain has this inhibitory mechanism, I think a lot of people are surprised to hear that recalling memories has this darker side of making us forget others by actually suppressing them.”
Patterns of brain activity in the participants were monitored by MRI scans while they were asked to recall individual memories based on images they had been shown earlier.
The researchers, co-led by Dr Michael Anderson, were able to track the brain activity induced by individual memories and show how this suppressed others by dividing the brain into tiny three-dimensional voxels.
• Secret behind why Alzheimer’s patients cannot make new memories discovered
Based on the fine-grained activation patterns of these voxels, the researchers were able to witness the neural fate of individual memories as they were reactivated initially, and subsequently suppressed. Over the course of four selective retrievals the participants in the study were cued to retrieve a target memory, which became more vivid with each trial.
Competing memories were less well reactivated as each trial was carried out, and in fact were pushed below baseline expectations for memory, supporting the idea that an active suppression of memory was taking place.
Source: http://www.telegraph.co.uk/news/science/science-news/11476423/If-you-remember-this-story-another-memory-will-die-off.html

Scientists’ New Goal: Growing Old Without Disease

Researchers plan to test a pill to prevent or delay Alzheimer’s, heart disease and other ailments that come with age

BRIAN HARKIN FOR THE WALL STREET JOURNAL
By SUMATHI REDDY
March 16, 2015 5:43 p.m. ET
Some of the top researchers on aging in the country are trying to get an unusual clinical trial up and running.
They want to test a pill that could prevent or delay some of the most debilitating diseases of old age, including Alzheimer’s and cardiovascular disease. The focus of the project isn’t to prolong life, although that could occur, but to make the last years or decades of people’s lives more fulfilling by postponing the onset of many chronic diseases until closer to death.
The project aims to tap into the growing body of research targeting aging, which has revealed a half dozen or more drugs that appear to delay the aging process in laboratory experiments on animals and observational studies of people. Some of the drugs also have been found to reduce the incidence of chronic diseases associated with old age.
“Aging is the major risk factor for all these diseases—heart disease, cancer, diabetes and Alzheimer’s,” said Nir Barzilai, director of the Institute for Aging Research at Albert Einstein College of Medicine in New York City who is leading the proposed study. “If you want to make a real impact you have to modulate the risk of aging and by that the risk for all those diseases of aging.”
ENLARGE
Dr. Barzilai expects to enroll more than 1,000 elderly participants in the randomized, controlled clinical trial to be conducted at multiple research centers and take five to seven years. The project is in the preliminary stages and permanent funding hasn’t yet been secured. Funding for the planning phase is coming from the American Federation for Aging Research, a nonprofit organization of which Dr. Barzilai is deputy scientific director.
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The trial aims to test the drug metformin, a common medication often used to treat Type 2 diabetes, and see if it can delay or prevent other chronic diseases. (The project is being called Targeting/Taming Aging With Metformin, or TAME.) Metformin isn’t necessarily more promising than other drugs that have shown signs of extending life and reducing age-related chronic diseases. But metformin has been widely and safely used for more than 60 years, has very few side effects and is inexpensive.
The scientists say that if TAME is a well-designed, large-scale study, the Food and Drug Administration might be persuaded to consider aging as an indication, or preventable condition, a move that could spur drug makers to target factors that contribute to aging.
A study that helped convince the gerontologists to pursue the TAME project was done in the U.K. and published last year in the journal Diabetes, Obesity and Metabolism. Researchers used data from a national registry of more than 180,000 people, comparing the treatment of metformin with that of sulfonylurea, another drug used for diabetes. They also created two control groups of nondiabetic people.
People who took metformin lived longer than those taking sulphonylurea, the study found. In addition, the people with diabetes who were 71-to-75-years-old at baseline and took metformin outlived their nondiabetic controls with a 15% greater survival rate.
“Observational studies like this are never definitive,” said Jill Crandall, director of the Diabetes Clinical Trials Unit at Albert Einstein College of Medicine and part of the TAME planning team. “But it is one of the observations that certainly supports our hypothesis—that certain pharmacological interventions, like metformin, may have broad effects in improving health and increasing health span.”
Dr. Crandall also participated in a federally funded study that found metformin and lifestyle changes were both effective in staving off diabetes in people at high risk for the disease for at least 10 years. Data from the study, which followed more than 3,000 adults for 15 years, are now being analyzed to see whether long-term use of metformin prevented the development of cardiovascular disease, cancer, cognitive decline and physical-function decline. The results could help in the planning of the TAME study, she said.
Dr. Barzilai, who is leading the effort to test if the drug metformin can delay or prevent chronic diseases, also focuses in his work on the genetics of centenarians. ENLARGE
Dr. Barzilai, who is leading the effort to test if the drug metformin can delay or prevent chronic diseases, also focuses in his work on the genetics of centenarians. PHOTO: BRIAN HARKIN FOR THE WALL STREET JOURNAL
Research has found that metformin targets the chemicals produced by age-related senescent cells—normal cells that stop dividing and produce toxic substances damaging to the cells around them, said James Kirkland, director of the Robert and Arlene Kogod Center on Aging at the Mayo Clinic in Rochester, Minn., and part of the TAME planning team. Senescent cells usually develop as people age or at sites of age-related chronic diseases, such as the brain in Alzheimer’s patients or around the plaques that lead to heart attacks and strokes, he said. It isn’t proven if senescent cells actually cause the disease.
Metformin appears also to slow the development of age-related symptoms by increasing the enzyme AMP kinase, which normally declines with age, and decreasing the protein mTOR, which helps to regulate cell growth.
Several other drugs also have shown life-extension properties in mice and in laboratory work, Dr. Kirkland said. His research group last week published a study on mice in the journal Aging Cell which showed that a combination of two drugs—dasatinib, a cancer drug, and quercetin, a supplement that can be found in health food stores—were potentially effective.
“There’s more and more evidence that by targeting aging itself we might be able to target these age-related chronic diseases that have been so intractable for us to try to come up with a cure for,” Dr. Kirkland said.
Fighting each major disease of old age separately isn’t winnable, said S. Jay Olshansky, another TAME project planner and a professor at the school of public health at the University of Illinois at Chicago. “We lower the risk of heart disease, somebody lives long enough to get cancer. If we reduce the risk of cancer, somebody lives long enough to get Alzheimer’s disease.”
“We are suggesting that the time has arrived to attack them all by going after the biological process of aging,” Dr. Olshansky said.
Sandy Walsh, an FDA spokeswoman, said the agency’s perspective has long been that “aging” isn’t a disease. “We clearly have approved drugs that treat consequences of aging,” she said. Although the FDA currently is inclined to treat diseases prevalent in older people as separate medical conditions, “if someone in the drug-development industry found something that treated all of these, we might revisit our thinking.”
Other experts agree with the goal of delaying chronic disease for the elderly, but question whether medication is the best way to do that. “I can certainly see how medicine can play a role if it turns out this study shows some promising findings,” said Alicia Arbaje, a geriatrician and an assistant professor of medicine at Johns Hopkins School of Medicine. “But aging is very complex and it’s probably going to take a multifaceted approach to help people delay or ensure that they age in a healthy way,” said Dr. Arbaje, who isn’t affiliated with the TAME trial planning.
Effective interventions to delay aging already exist, Dr. Arbaje noted, such as exercise, nutrition, social engagement, stress reduction and getting adequate sleep. “These are reliable and effective ways to keep people healthy as they age,” she said. “The problem is they’re not as easy as taking a medication.”
Write to Sumathi Reddy at sumathi.reddy@wsj.comBrian Harkin for the Wall Street Journal

Physical Therapy For Back Pain

 
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Source: http://depothealth.com/pain/physical-therapy-for-back-pain/